pentobarbital will minimize the extent or impact of saxagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.
pentobarbital will decrease the level or impact of itraconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.
pentobarbital will decrease the extent or outcome of vincristine liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.
Remark: Barbiturates may increase adverse effects, such as respiratory depression, produced by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates raise metabolism and decrease blood concentrations of TCAs.
Remark: Barbiturates may perhaps increase adverse effects, such as respiratory depression, produced by poisonous doses of TCAs. With therapeutic doses of TCAs, barbiturates maximize metabolism and reduce blood concentrations of TCAs.
Contraindicated (one)pentobarbital will lessen the extent or impact of dienogest/estradiol valerate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Girls should not select estradiol valerate/dienogest as their contraceptive although employing potent CYP3A4 inducers as a result of likely lower in contraceptive efficacy.
Contraindicated (one)pentobarbital will minimize the level or influence of cobimetinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay away from coadministration. Sturdy or average CYP3A inducers may reduce cobimetinib systemic exposure by >eighty% and decrease its efficacy.
pentobarbital will lower the extent or influence of pazopanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will reduce the extent or effect of get more info sunitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lower the level or impact of diclofenac by impacting hepatic enzyme CYP2C9/ten metabolism. Minor/Importance Not known.
pentobarbital will lower the extent or outcome of cortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will minimize the extent or impact of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or influence of nimodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.
pentobarbital will reduce the extent or outcome of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Lack of, or decreased response to tofacitinib may well occur when coadministered with powerful CYP3A4 inducers